Sample to Sequence Undergraduate Course

Sample to Sequence is an upper-level undergraduate laboratory-based course taught at HudsonAlpha. It introduces the excitement of scientific discovery as well as the practical challenges of applying DNA sequencing technology to address real-world questions.


Sample to Sequence is a three credit-hour course offered to students at The University of Alabama in Huntsville, Athens State University and Alabama Agricultural and Mechanical University. Students work as part of a research team under direct supervision of seasoned instructors to define the metagenomic profile of environmental samples. Many of the critical skills commonly used in biotechnology are covered, including:

  • sampling and handling biological specimens
  • extracting, amplifying and sequencing DNA
  • utilizing bioinformatics databases to identify organisms on the basis of DNA sequence variation
  • linking DNA variation to biological diversity


The course is taught Fall and Spring semesters, and requires approximately 9 hours of laboratory work each week.
Now enrolling for Fall 2014 to Fall 2015. Interested students should contact Dr. Bob Zahorchak at