This unique facility leverages front-line genetic research tools for HudsonAlpha’s scientists and extends them to global academic institutions as well as commercial clients. Under the direction of Shawn Levy, the CLIA-certified GSL has established its expertise in high-throughput sequencing and optimizing workflows and analytical pipelines.
The GSL has supported more than 1,100 projects and more than 30,000 samples since beginning in 2009. These projects have been in collaboration with colleagues from HudsonAlpha and from hundreds of laboratories around the world. The GSL continually strengthens its technical capabilities and routinely collaborates with many of the major technology vendors to improve the performance and efficiency of genomic technologies.
In addition to the technologies used by GSL, the laboratory has a dedicated bioinformatics and analysis group to ensure that data produced in the lab is analyzed and interpreted to the highest quality and most significant impact result. Today, the GSL operates more than a dozen high-performance sequencing instruments representing all major technologies. The large sequencing capacity coupled with a professional staff with extensive genomics and informatics experience allows the GSL to support projects of nearly any size and scope.
The results and capabilities of the GSL are being used to develop novel healthcare screening products and diagnostic products, as well as to direct research and clinical trials for the improvement of human health. Data produced in the GSL has revealed the genetic causes of more than 10 inherited diseases and is contributing to the understanding of complex disorders such as autism, ALS, bipolar disorder, schizophrenia, diabetes and other diseases.